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In the headlines

-  Thesis proposals are available at the LRSV. The subjects are available on the "adum" database (here). Candidates will be selected for the competition organized by the doctoral school SEVAB to obtain a 3 years doctoral contract.

- Jean-Philippe Combier recipient of a CNRS Bronze Medal 2016 ! The CNRS awards Jean-Philippe Combier, a LRSV CNRS researcher the bronze Medal for his work on micro-RNA encoded peptides (MiPep).

- The BioPlantProduct laboratory between LRSV and the DE SANGOSSE company (2015-2017)

BioPlantProduct aims at developing a collaborative research platform involving LRSV and DE SANGOSSE (Agen, France), a company which develops and commercializes products for crop protection. This project is supported by ANR.

The future of agriculture will require the development of new environmental-friendly agronomical strategies and safe for the consumers. Among these strategies, the development of products issued from natural sources to protect crops against biotic stresses and weeds (biocontrol products), will contribute to decrease the use of chemical pesticides. A major source of these natural products will be the microbial population living in the natural environment of plants in the soil (rhizosphere) or on the aerial plant tissues (phyllosphere) which contribute to the resistance of plants to microbial pathogens. Research projects conducted in the frame of BioPlantProtec will aim to identify and to select beneficial microbial strains, displaying a protective activity against plant diseases. A complementary aspect will be identifying microbial strains showing herbicidal activity against selected weeds. Candidates will be selected for industrial development (industrial production, formulation, field tests) by the industrial partner.

The scientific and technical program of BioPlantProtec will include the development of high-throughput screening tools to select active strains, to studies their mode of action and to follow their behavior on the field. The identification and characterization of the most promising candidates will lay on the use of available technologies provided by the LRSV, including metabolomics (mass spectrometry, nuclear magnetic resonance), genomics, transciptomics and cellular imaging. The protocols developed in the frame of BioPlantProtec will be also useful to help the industrial development of the products and to optimize their use. In parallel, projects targeted on some crop diseases will be defined in the beginning of the program, taking into account the market of biocontrol products on these diseases or weeds. Previous studies at LRSV have shown the interest of these tools to identify active compounds, some of these being the subject of industrial development. BioPlantProtec will mainly involve the LRSV Plant-Microbe Interactions team which develops researches on oomycete and fungal pathogenicity and on the plant immune system. Il will also beneficiate of the expertise of the other LRSV teams which conduct studies on symbiotic microorganisms, plant development and cell signaling.

BioPlantProtec will bring to the private partner new scientific and technological expertise which will be complementary to the other steps needed to launch new biocontrol products, and will offer to LRSV a unique opportunity to validate in fields results and concepts issued from fundamental studies.

- The LRSV and the "French excellence initiative" projects :

* Our laboratory belongs to the TULIP LabEx : Towards a Unified theory of biotic Interactions : the roLe of environmental Perturbations.

The TULIP Labex project was selected during the first wave of the "French excellence initiative",TULIP . Winner in the category of "LABoratory of EXcellence" or LabEx", it will anchor in Midi-Pyrenees a high quality research and education team in the field of ecology and plant biology.

In addition to LRSV, this project groups 4 laboratories : LIPM (Laboratory of Plant-Microbe Interactions, UMR 2594/441 CNRS/INRA), EDB (Evolution and Biological Diversity, UMR 5174 UPS/CNRS/ENFA), GBF (Genomic and Biotechnology of the Fruit, UMR 990 INRA/INP-ENSAT) et SEEM (Station d’Ecologie Experimentale du CNRS à Moulis, USR 2936 CNRS/UPS).

* The French MetaboHUB project aims at creating a national infrastructure of metabolomics that will place France among the European leaders for advanced research services in metabolomics and fluxomics. This infrastructure will provide tools and services to academic research teams and industrial partners in the fields of nutrition and health, agriculture and biotechnologies. It groups four metabolomics and fluxomics existing platforms located in Bordeaux, Clermont-Ferrand, Saclay and Toulouse.

MetaboHUB Infrastructure will address major life science trends and challenges listed in the National Strategy for Research and Innovation priorities. MetaboHUB outputs will provide full service, (i) relevant biomarkers for personalized nutrition and personalized medicine and diagnosis of diseases with major socio-economic impact such as obesity, cancer, cardiovascular, neurological pathologies and infectious diseases (ii) stress indicators and biomarkers for plant and animal breeding programs and agricultural practices, and (iii) new tools to optimize microbial metabolic engineering and create new synthesis pathway with industrial applications and (iV) complements to other ‘omics’ technologies data to support systems biology approach.

The LRSV hosts the Plant secondary metabolites platform which belongs to the Toulouse MetaToul facility.

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