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Accueil du site > Equipes de recherche > Peroxydases : évolution et expression > Thèmes de recherche > Evolutive analysis of class III peroxidases

Evolutive analysis of class III peroxidases

Contact : mail to Catherine MATHÉ and mail to Christophe DUNAND

Background
Peroxidases of class III or secreted peroxidases from plants have the characteristic of belonging to a large multigene family (73 in Arabidopsis thaliana and 138 in Oryza sativa). They are specific from plants and absent from Chlamydomonas (Chlorophyceae) and show a high rate of duplications in late divergente plants versus early divergente plants. This high rate of duplications, phylum or gender dependent, as well as gene gain and loss events, makes the evolutionary studies complex.

Objectives
The comprehensive annotation of peroxidases from various plant representatives whose genomes are completely sequenced (Brachypodium, rice, Arabidopsis, sorghum, poplar ...) would help to identify orthologs and events of gains and losses of genes.
Tools for sequence clustering (as orthoMCL) and reconstruction of ancestral sequences will be used to facilitate analysis.
Thus, an overall phylogenetic analysis of peroxidases in the green lineage, completed by the comparison of their gene structure and genomic organization, should allow us to understand the evolution of this complex family.

Phylogenetic tree of Class III peroxidases from Selaginella (85 seq), Arabidopsis (73 seq) and Rice (138 seq)